The calculated distance (air line) between Tlaltizapán and Ciudad Nezahualcoyotl is approximately 50 miles respectively 80 kilometers.
By car or train, the actual journey to Ciudad Nezahualcoyotl is certainly longer, as only the direct route (as the crow flies) between Tlaltizapán and Ciudad Nezahualcoyotl has been calculated here.
Air line (approximately)
80 kilometers
43 nautical miles